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Sulodexide Decreases Albuminuria and Regulates Matrix Protein Accumulation in C57BL/6 Mice with Streptozotocin-Induced Type I Diabetic Nephropathy

OBJECTIVE: Sulodexide is a mixture of glycosaminoglycans that may reduce proteinuria in diabetic nephropathy (DN), but its mechanism of action and effect on renal histology is not known. We investigated the effect of sulodexide on disease manifestations in a murine model of type I DN. METHODS: Male...

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Detalles Bibliográficos
Autores principales:	Yung, Susan, Chau, Mel K. M., Zhang, Qing, Zhang, Chen Zhu, Chan, Tak Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551764/ https://www.ncbi.nlm.nih.gov/pubmed/23349910 http://dx.doi.org/10.1371/journal.pone.0054501

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