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Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis
BACKGROUND: Rheumatoid arthritis is a disease affecting the extracellular matrix of especially synovial joints. The thickness of the synovial membrane increases and surrounding tissue degrades, leading to altered collagen balance in the tissues. In this study, we investigated the altered tissue bala...
Autores principales: | Siebuhr, Anne Sofie, Wang, Jianxia, Karsdal, Morten, Bay-Jensen, Anne-C, Y, Jin, Q, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551788/ https://www.ncbi.nlm.nih.gov/pubmed/22992383 http://dx.doi.org/10.1186/1479-5876-10-195 |
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