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Improved Discovery of Molecular Interactions in Genome-Scale Data with Adaptive Model-Based Normalization
BACKGROUND: High throughput molecular-interaction studies using immunoprecipitations (IP) or affinity purifications are powerful and widely used in biology research. One of many important applications of this method is to identify the set of RNAs that interact with a particular RNA-binding protein (...
Autores principales: | Salzman, Julia, Klass, Daniel M., Brown, Patrick O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551948/ https://www.ncbi.nlm.nih.gov/pubmed/23349766 http://dx.doi.org/10.1371/journal.pone.0053930 |
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