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Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

Caloric restriction (CR), a reduction of food intake while avoiding malnutrition, can delay the onset of cancer and age-related diseases in several species, including mice. In addition, depending of the genetic background, CR can also increase or decrease mouse longevity. This has highlighted the im...

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Detalles Bibliográficos
Autores principales: Vera, Elsa, Bernardes de Jesus, Bruno, Foronda, Miguel, Flores, Juana M., Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551964/
https://www.ncbi.nlm.nih.gov/pubmed/23349740
http://dx.doi.org/10.1371/journal.pone.0053760