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Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism
Improving the control of energy homeostasis can lower cardiovascular risk in metabolically compromised individuals. To identify new regulators of whole-body energy control, we conducted a high-throughput screen in transgenic reporter zebrafish for small molecules that modulate the expression of the...
Autores principales: | Gut, Philipp, Baeza-Raja, Bernat, Andersson, Olov, Hasenkamp, Laura, Hsiao, Joseph, Hesselson, Daniel, Akassoglou, Katerina, Verdin, Eric, Hirschey, Matthew D., Stainier, Didier Y.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552031/ https://www.ncbi.nlm.nih.gov/pubmed/23201900 http://dx.doi.org/10.1038/nchembio.1136 |
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