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Skin Involvement in Primary Systemic Amyloidosis
Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552729/ https://www.ncbi.nlm.nih.gov/pubmed/23350018 http://dx.doi.org/10.4084/MJHID.2013.005 |
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author | Kumar, Susheel Sengupta, Rimi Som Kakkar, Nandita Sharma, Aman Singh, Surjit Varma, Subhash |
author_facet | Kumar, Susheel Sengupta, Rimi Som Kakkar, Nandita Sharma, Aman Singh, Surjit Varma, Subhash |
author_sort | Kumar, Susheel |
collection | PubMed |
description | Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form of skin manifestations. |
format | Online Article Text |
id | pubmed-3552729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Università Cattolica del Sacro Cuore |
record_format | MEDLINE/PubMed |
spelling | pubmed-35527292013-01-24 Skin Involvement in Primary Systemic Amyloidosis Kumar, Susheel Sengupta, Rimi Som Kakkar, Nandita Sharma, Aman Singh, Surjit Varma, Subhash Mediterr J Hematol Infect Dis Case Report Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form of skin manifestations. Università Cattolica del Sacro Cuore 2013-01-02 /pmc/articles/PMC3552729/ /pubmed/23350018 http://dx.doi.org/10.4084/MJHID.2013.005 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kumar, Susheel Sengupta, Rimi Som Kakkar, Nandita Sharma, Aman Singh, Surjit Varma, Subhash Skin Involvement in Primary Systemic Amyloidosis |
title | Skin Involvement in Primary Systemic Amyloidosis |
title_full | Skin Involvement in Primary Systemic Amyloidosis |
title_fullStr | Skin Involvement in Primary Systemic Amyloidosis |
title_full_unstemmed | Skin Involvement in Primary Systemic Amyloidosis |
title_short | Skin Involvement in Primary Systemic Amyloidosis |
title_sort | skin involvement in primary systemic amyloidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552729/ https://www.ncbi.nlm.nih.gov/pubmed/23350018 http://dx.doi.org/10.4084/MJHID.2013.005 |
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