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Porous silicon-based nanostructured microparticles as degradable supports for solid-phase synthesis and release of oligonucleotides
We describe the preparation of several types of porous silicon (pSi) microparticles as supports for the solid-phase synthesis of oligonucleotides. The first of these supports facilitates oligonucleotide release from the nanostructured support during the oligonucleotide deprotection step, while the s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552826/ https://www.ncbi.nlm.nih.gov/pubmed/22784812 http://dx.doi.org/10.1186/1556-276X-7-385 |