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Hypoxia, MTOR and autophagy: Converging on senescence or quiescence
Although hypoxia can cause cell cycle arrest, it may simultaneously suppress a conversion from this arrest to senescence. Furthermore, hypoxia can suppress senescence caused by diverse stimuli, maintaining reversible quiescence instead. Hypoxia activates autophagy and inhibits MTOR, thus also activa...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552896/ https://www.ncbi.nlm.nih.gov/pubmed/23192222 http://dx.doi.org/10.4161/auto.22783 |