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Tissue-specific expression of p73 C-terminal isoforms in mice
p73 is a p53 family transcription factor. Due to the presence in the 5′ flanking region of two promoters, there are two N-terminal variants, TAp73, which retains a fully active transactivation domain (TA), and ΔNp73, in which the N terminus is truncated. In addition, extensive 3′ splicing gives rise...
Autores principales: | Grespi, Francesca, Amelio, Ivano, Tucci, Paola, Annicchiarico-Petruzzelli, Margherita, Melino, Gerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552929/ https://www.ncbi.nlm.nih.gov/pubmed/23159862 http://dx.doi.org/10.4161/cc.22787 |
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