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The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients
BACKGROUND: The minor allele of SNP rs3803662 has been shown to correlate with increased breast cancer risk and with lower expression of TOX3. The SNP is closely located to TOX3 residing within an uncharacterised gene LOC643714. The aim of the study was to examine the association of the risk allele...
Autores principales: | Gudmundsdottir, Eydis Th, Barkardottir, Rosa B, Arason, Adalgeir, Gunnarsson, Haukur, Amundadottir, Laufey Th, Agnarsson, Bjarni A, Johannsson, Oskar Th, Reynisdottir, Inga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553017/ https://www.ncbi.nlm.nih.gov/pubmed/23270421 http://dx.doi.org/10.1186/1471-2407-12-621 |
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