Cargando…

MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma

BACKGROUND: MicroRNAs are short regulatory RNAs that negatively modulate protein expression at a post-transcriptional and/or translational level and are deeply involved in the pathogenesis of several types of cancers. Specifically, microRNA-221 (miR-221) is overexpressed in many human cancers, where...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Guangyi, Cai, Chengkui, Yang, Tongtao, Qiu, Xiuchun, Liao, Bo, Li, Wei, Ji, Zhenwei, Zhao, Jian, Zhao, Haien, Guo, Mingjun, Ma, Qiong, Xiao, Chun, Fan, Qingyu, Ma, Baoan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553141/ https://www.ncbi.nlm.nih.gov/pubmed/23372675 http://dx.doi.org/10.1371/journal.pone.0053906

Ejemplares similares

Correction: MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma
por: Zhao, Guangyi, et al.
Publicado: (2013)

miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells
por: ZHAO, HAIEN, et al.
Publicado: (2012)

Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma
por: Guo, Mingjun, et al.
Publicado: (2014)

MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo
por: Yan, Kang, et al.
Publicado: (2012)

microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting CDH2 and IGF1R
por: HAN, KANG, et al.
Publicado: (2014)

MicroRNA profiling identifies MiR-195 suppresses osteosarcoma cell metastasis by targeting CCND1
por: Han, Kang, et al.
Publicado: (2015)

Post-Operative Auto-Transfusion in Total Hip or Knee Arthroplasty: A Meta-Analysis of Randomized Controlled Trials
por: Haien, Zhao, et al.
Publicado: (2013)

MicroRNA-221 promotes cisplatin resistance in osteosarcoma cells by targeting PPP2R2A
por: Yu, Wen-chao, et al.
Publicado: (2019)

MicroRNA-22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway
por: Meng, Chen-Yang, et al.
Publicado: (2020)

Correction: MicroRNA-221 promotes cisplatin resistance in osteosarcoma cells by targeting PPP2R2A
Publicado: (2022)

Interleukin-6 suppression reduces tumour self-seeding by circulating tumour cells in a human osteosarcoma nude mouse model
por: Zhang, Yinglong, et al.
Publicado: (2015)

MicroRNA-221 Modulates Airway Remodeling via the PI3K/AKT Pathway in OVA-Induced Chronic Murine Asthma
por: Pan, Jing, et al.
Publicado: (2020)

MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis
por: YAN, SHIJU, et al.
Publicado: (2016)

Functional role of MicroRNA/PI3K/AKT axis in osteosarcoma
por: Xiang, Yubo, et al.
Publicado: (2023)

MicroRNA-22 regulates autophagy and apoptosis in cisplatin resistance of osteosarcoma
por: Meng, Chen-Yang, et al.
Publicado: (2020)

Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221
por: Zhang, Jianjun, et al.
Publicado: (2016)

Immunologic Response to Tumor Ablation with Irreversible Electroporation
por: Li, Xiaoxiang, et al.
Publicado: (2012)

MicroRNA-761 targets FGFR1 to suppress the malignancy of osteosarcoma by deactivating PI3K/Akt pathway
por: Lv, Zhongzhe, et al.
Publicado: (2019)

Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway
por: Liu, Bing, et al.
Publicado: (2017)

Is Limb Salvage With Microwave-induced Hyperthermia Better Than Amputation for Osteosarcoma of the Distal Tibia?
por: Han, Kang, et al.
Publicado: (2017)

Self-seeding circulating tumor cells promote the proliferation and metastasis of human osteosarcoma by upregulating interleukin-8
por: Liu, Tao, et al.
Publicado: (2019)

The Effects of Irreversible Electroporation (IRE) on Nerves
por: Li, Wei, et al.
Publicado: (2011)

Knockdown of Akt Sensitizes Osteosarcoma Cells to Apoptosis Induced by Cisplatin Treatment
por: Zhang, Guoyou, et al.
Publicado: (2011)

Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis
por: Liu, Liang, et al.
Publicado: (2021)

Expression of MDR1, HIF-1α and MRP1 in sacral chordoma and chordoma cell line CM-319
por: Ji, Zhengang, et al.
Publicado: (2010)

Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer
por: Li, Nannan, et al.
Publicado: (2019)

microRNA-mediated GAS1 downregulation promotes the proliferation of synovial fibroblasts by PI3K-Akt signaling in osteoarthritis
por: Dong, Chuan, et al.
Publicado: (2019)

MicroRNA-340-5p modulates cisplatin resistance by targeting LPAATβ in osteosarcoma
por: Song, L., et al.
Publicado: (2017)

MicroRNA-939-5p directly targets IGF-1R to inhibit the aggressive phenotypes of osteosarcoma through deactivating the PI3K/Akt pathway
por: Zhao, Xiwu, et al.
Publicado: (2019)

MicroRNA-939-5p directly targets IGF-1R to inhibit the aggressive phenotypes of osteosarcoma through deactivating the PI3K/Akt pathway
por: Zhao, Xiwu, et al.
Publicado: (2022)

Fresh-frozen Complete Extensor Mechanism Allograft versus Autograft Reconstruction in Rabbits
por: Chen, Guanyin, et al.
Publicado: (2016)

Hedgehog/GLI1 signaling pathway regulates the resistance to cisplatin in human osteosarcoma
por: Chen, Daosen, et al.
Publicado: (2021)

MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway
por: Qiu, Chensheng, et al.
Publicado: (2020)

Overexpression of GATA4 enhances the antiapoptotic effect of exosomes secreted from cardiac colony-forming unit fibroblasts via miRNA221-mediated targeting of the PTEN/PI3K/AKT signaling pathway
por: Hao, Chunshu, et al.
Publicado: (2020)

DPY30 promotes the growth and survival of osteosarcoma cells by regulating the PI3K/AKT signal pathway
por: Cheng, Gong, et al.
Publicado: (2022)

Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway
por: Li, Hong-Bo, et al.
Publicado: (2021)

Silencing XIAP suppresses osteosarcoma cell growth, and enhances the sensitivity of osteosarcoma cells to doxorubicin and cisplatin
por: Qu, Yang, et al.
Publicado: (2022)

Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway
por: Huang, Fang, et al.
Publicado: (2019)

Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer
por: Kou, Yingying, et al.
Publicado: (2020)

Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway
por: Zhao, Xin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ftvn1ng24nslb77al1522kijt1