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Down-Regulation of CTLA-4 by HIV-1 Nef Protein

HIV-1 Nef protein down-regulates several cell surface receptors through its interference with the cell sorting and trafficking machinery. Here we demonstrate for the first time the ability of Nef to down-regulate cell surface expression of the negative immune modulator CTLA-4. Down-regulation of CTL...

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Detalles Bibliográficos
Autores principales:	El-Far, Mohamed, Isabelle, Catherine, Chomont, Nicolas, Bourbonnière, Martin, Fonseca, Simone, Ancuta, Petronela, Peretz, Yoav, Chouikh, Younes, Halwani, Rabih, Schwartz, Olivier, Madrenas, Joaquín, Freeman, Gordon J., Routy, Jean-Pierre, Haddad, Elias K., Sékaly, Rafick-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553160/ https://www.ncbi.nlm.nih.gov/pubmed/23372701 http://dx.doi.org/10.1371/journal.pone.0054295

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