Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages

BACKGROUND: HIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases. We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammatory response through inhibiting endoplasmic retic...

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Detalles Bibliográficos
Autores principales: Zha, Weibin, Wang, Guangji, Xu, Weiren, Liu, Xuyuan, Wang, Yun, Zha, Beth S., Shi, Jian, Zhao, Qijin, Gerk, Phillip M., Studer, Elaine, Hylemon, Phillip B., Pandak, William M., Zhou, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553168/
https://www.ncbi.nlm.nih.gov/pubmed/23372711
http://dx.doi.org/10.1371/journal.pone.0054349

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