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The (pro)renin receptor. A decade of research: what have we learned?

The discovery of a (pro)renin receptor ((P)RR) in 2002 provided a long-sought explanation for tissue renin–angiotensin system (RAS) activity and a function for circulating prorenin, the inactive precursor of renin, in end-organ damage. Binding of renin and prorenin (referred to as (pro)renin) to the...

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Detalles Bibliográficos
Autores principales: Krop, Manne, Lu, Xifeng, Danser, A.H. Jan, Meima, Marcel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553411/
https://www.ncbi.nlm.nih.gov/pubmed/22543358
http://dx.doi.org/10.1007/s00424-012-1105-z