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Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation

PURPOSE: To improve the delivery of liposomes to tumors using P-selectin glycoprotein ligand 1 (PSGL1) mediated binding to selectin molecules, which are upregulated on tumorassociated endothelium. METHODS: PSGL1 was orientated and presented on the surface of liposomes to achieve optimal selectin bin...

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Detalles Bibliográficos
Autores principales:	Carlisle, Robert, Seymour, Leonard W., Coussios, Constantin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553414/ https://www.ncbi.nlm.nih.gov/pubmed/22992830 http://dx.doi.org/10.1007/s11095-012-0875-5

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