Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice

Background: Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in persons with type 2 diabetes. Objectives: We investigated the i...

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Detalles Bibliográficos
Autores principales: Baker, Nicki A., Karounos, Michael, English, Victoria, Fang, Jun, Wei, Yinan, Stromberg, Arnold, Sunkara, Manjula, Morris, Andrew J., Swanson, Hollie I., Cassis, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553436/
https://www.ncbi.nlm.nih.gov/pubmed/23099484
http://dx.doi.org/10.1289/ehp.1205421

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