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Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients

BACKGROUND: Prostate cancer cell growth is dependent upon androgen receptor (AR) activation, which is regulated by specific kinases. The aim of the current study is to establish if AR phosphorylation by Cdk1 or ERK1/2 is of prognostic significance. METHODS: Scansite 2.0 was utilised to predict which...

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Detalles Bibliográficos
Autores principales:	Willder, J M, Heng, S J, McCall, P, Adams, C E, Tannahill, C, Fyffe, G, Seywright, M, Horgan, P G, Leung, H Y, Underwood, M A, Edwards, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553508/ https://www.ncbi.nlm.nih.gov/pubmed/23321516 http://dx.doi.org/10.1038/bjc.2012.480

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