Cargando…

Radiation induced COX-2 expression and mutagenesis at non-targeted lung tissues of gpt delta transgenic mice

BACKGROUND: Although radiation-induced bystander effects have been confirmed using a variety of endpoints, the mechanism(s) underlying these effects are not well understood, especially for in vivo study. METHODS: A 1-cm(2) area (1 cm × 1 cm) in the lower abdominal region of gpt delta transgenic mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chai, Y, Calaf, G M, Zhou, H, Ghandhi, S A, Elliston, C D, Wen, G, Nohmi, T, Amundson, S A, Hei, T K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553512/ https://www.ncbi.nlm.nih.gov/pubmed/23321513 http://dx.doi.org/10.1038/bjc.2012.498

Ejemplares similares

Radiation-induced non-targeted response in vivo: role of the TGFβ-TGFBR1-COX-2 signalling pathway
por: Chai, Y, et al.
Publicado: (2013)

Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells
por: Xu, An, et al.
Publicado: (2009)

Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents
por: Masumura, Kenichi, et al.
Publicado: (2015)

New Insight into Intrachromosomal Deletions Induced by Chrysotile in the gpt delta Transgenic Mutation Assay
por: Xu, An, et al.
Publicado: (2007)

Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta
por: Nohmi, Takehiko, et al.
Publicado: (2021)

Connexins and cyclooxygenase-2 crosstalk in the expression of radiation-induced bystander effects
por: Zhao, Y, et al.
Publicado: (2014)

New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay
por: Masumura, Kenichi, et al.
Publicado: (2021)

Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects
por: Chen, S, et al.
Publicado: (2008)

Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer
por: Jubb, A M, et al.
Publicado: (2009)

Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue
por: Charalambous, M P, et al.
Publicado: (2009)

Transgenic rat models for mutagenesis and carcinogenesis
por: Nohmi, Takehiko, et al.
Publicado: (2017)

Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence
por: Barnes, N, et al.
Publicado: (2006)

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
por: Kurosu, T, et al.
Publicado: (2011)

Radiation dose-rate effects on gene expression for human biodosimetry
por: Ghandhi, Shanaz A., et al.
Publicado: (2015)

Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2
por: Hickman, Oliver J, et al.
Publicado: (2016)

Human thyroid tumours, the puzzling lessons from E7 and RET/PTC3 transgenic mice
por: Jin, L, et al.
Publicado: (2008)

Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect
por: Yang, G, et al.
Publicado: (2009)

Targeting of Rad51-dependent homologous recombination: implications for the radiation sensitivity of human lung cancer cell lines
por: Sak, A, et al.
Publicado: (2005)

Differential tissue-specific protein markers of vaginal carcinoma
por: Hellman, K, et al.
Publicado: (2009)

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling
por: Atrih, A, et al.
Publicado: (2014)

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion
por: Dominek, P, et al.
Publicado: (2010)

GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics
por: Kristiansen, G, et al.
Publicado: (2008)

EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors?
por: Paliga, A, et al.
Publicado: (2012)

Effects of the scid mutation on X-ray-induced deletions in the brain and spleen of gpt delta mice
por: Masumura, Kenichi, et al.
Publicado: (2020)

Absence of a specific radiation signature in post-Chernobyl thyroid cancers
por: Detours, V, et al.
Publicado: (2005)

Increased expression of pAKT is associated with radiation resistance in cervical cancer
por: Kim, T-J, et al.
Publicado: (2006)

Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice
por: Aoki, Yasunobu, et al.
Publicado: (2021)

Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area
por: Aoki, Yasunobu, et al.
Publicado: (2018)

Aberrant CDKN1A transcriptional response associates with abnormal sensitivity to radiation treatment
por: Badie, C, et al.
Publicado: (2008)

Fluorescence in situ hybridisation analysis of chromosomal aberrations in gastric tissue: the potential involvement of Helicobacter pylori
por: Williams, L, et al.
Publicado: (2005)

Lymph node tissue kallikrein-related peptidase 6 mRNA: a progression marker for colorectal cancer
por: Ohlsson, L, et al.
Publicado: (2012)

Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma
por: Birgersdotter, A, et al.
Publicado: (2009)

Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients
por: Szkandera, J, et al.
Publicado: (2013)

MicroRNA profiling in clear cell renal cell carcinoma tissues potentially links tumorigenesis and recurrence with obesity
por: Shu, X, et al.
Publicado: (2017)

Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients
por: Taubert, H, et al.
Publicado: (2010)

The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue
por: Oladipo, O, et al.
Publicado: (2011)

Expression of pendrin in benign and malignant human thyroid tissues
por: Skubis-Zegadło, J, et al.
Publicado: (2005)

Diagnostic potential of near-infrared Raman spectroscopy in the stomach: differentiating dysplasia from normal tissue
por: Teh, S K, et al.
Publicado: (2008)

Tamoxifen resistance in early breast cancer: statistical modelling of tissue markers to improve risk prediction
por: Baneshi, M R, et al.
Publicado: (2010)

Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats
por: Akagi, Jun-ichi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_pjob51oos24dclbofl1jldgoqj