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Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
BACKGROUND: Regulatory T cells (Tregs) are commonly identified by expression of the transcription factor FOXP3 and are conventionally thought to promote cancer progression by suppressing anti-tumour immune responses. We examined the relationship between FOXP3(+) tumour-infiltrating lymphocytes (TIL)...
Autores principales: | West, N R, Kost, S E, Martin, S D, Milne, K, deLeeuw, R J, Nelson, B H, Watson, P H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553524/ https://www.ncbi.nlm.nih.gov/pubmed/23169287 http://dx.doi.org/10.1038/bjc.2012.524 |
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