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Recognition of the mycobacterial cord factor by Mincle: relevance for granuloma formation and resistance to tuberculosis
The world's most successful intracellular bacterial pathogen, Mycobacterium tuberculosis (MTB), survives inside macrophages by blocking phagosome maturation and establishes chronic infection characterized by the formation of granulomas. Trehalose-6,6-dimycolate (TDM), the mycobacterial cord fac...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553576/ https://www.ncbi.nlm.nih.gov/pubmed/23355839 http://dx.doi.org/10.3389/fimmu.2013.00005 |