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Recognition of the mycobacterial cord factor by Mincle: relevance for granuloma formation and resistance to tuberculosis

The world's most successful intracellular bacterial pathogen, Mycobacterium tuberculosis (MTB), survives inside macrophages by blocking phagosome maturation and establishes chronic infection characterized by the formation of granulomas. Trehalose-6,6-dimycolate (TDM), the mycobacterial cord fac...

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Detalles Bibliográficos
Autor principal: Lang, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553576/
https://www.ncbi.nlm.nih.gov/pubmed/23355839
http://dx.doi.org/10.3389/fimmu.2013.00005