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C-terminal low-complexity sequence repeats of Mycobacterium smegmatis Ku modulate DNA binding

Ku protein is an integral component of the NHEJ (non-homologous end-joining) pathway of DSB (double-strand break) repair. Both eukaryotic and prokaryotic Ku homologues have been characterized and shown to bind DNA ends. A unique feature of Mycobacterium smegmatis Ku is its basic C-terminal tail that...

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Detalles Bibliográficos
Autores principales: Kushwaha, Ambuj K., Grove, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553676/
https://www.ncbi.nlm.nih.gov/pubmed/23167261
http://dx.doi.org/10.1042/BSR20120105