Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

The degradation of most eukaryotic mRNAs is initiated by removal of the poly(A) tail, and the major deadenylase activity is associated with the CCR4/CAF1/NOT complex (NOT complex). We here study the role of CNOT10, a protein that is found in human and trypanosome, but not in yeast, NOT complexes. Tr...

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Detalles Bibliográficos
Autores principales: Färber, Valentin, Erben, Esteban, Sharma, Sahil, Stoecklin, Georg, Clayton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553956/
https://www.ncbi.nlm.nih.gov/pubmed/23221646
http://dx.doi.org/10.1093/nar/gks1133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553956/
https://www.ncbi.nlm.nih.gov/pubmed/23221646
http://dx.doi.org/10.1093/nar/gks1133

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