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Detection of alternative lengthening of telomeres by telomere quantitative PCR

Alternative lengthening of telomeres (ALT) is one of the two known telomere length maintenance mechanisms that are essential for the unlimited proliferation potential of cancer cells. Existing methods for detecting ALT in tumors require substantial amounts of tumor material and are labor intensive,...

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Detalles Bibliográficos
Autores principales: Lau, Loretta M. S., Dagg, Rebecca A., Henson, Jeremy D., Au, Amy Y. M., Royds, Janice A., Reddel, Roger R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553966/
https://www.ncbi.nlm.nih.gov/pubmed/22923525
http://dx.doi.org/10.1093/nar/gks781