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Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome

Ribosomal subunit biogenesis in eukaryotes is a complex multistep process. Mrd1 is an essential and conserved small (40S) ribosomal subunit synthesis factor that is required for early cleavages in the 35S pre-ribosomal RNA (rRNA). Yeast Mrd1 contains five RNA-binding domains (RBDs), all of which are...

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Detalles Bibliográficos
Autores principales:	Segerstolpe, Åsa, Granneman, Sander, Björk, Petra, de Lima Alves, Flavia, Rappsilber, Juri, Andersson, Charlotta, Högbom, Martin, Tollervey, David, Wieslander, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553979/ https://www.ncbi.nlm.nih.gov/pubmed/23193268 http://dx.doi.org/10.1093/nar/gks1129

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