Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation

Gene expression profiles can be used to infer previously unknown transcriptional regulatory interaction among thousands of genes, via systems biology ‘reverse engineering’ approaches. We ‘reverse engineered’ an embryonic stem (ES)-specific transcriptional network from 171 gene expression profiles, m...

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Detalles Bibliográficos
Autores principales: De Cegli, Rossella, Iacobacci, Simona, Flore, Gemma, Gambardella, Gennaro, Mao, Lei, Cutillo, Luisa, Lauria, Mario, Klose, Joachim, Illingworth, Elizabeth, Banfi, Sandro, di Bernardo, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553984/
https://www.ncbi.nlm.nih.gov/pubmed/23180766
http://dx.doi.org/10.1093/nar/gks1136

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