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Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle

Spinal muscular atrophy is a severe motor neuron disease caused by reduced levels of the ubiquitous Survival of MotoNeurons (SMN) protein. SMN is part of a complex that is essential for spliceosomal UsnRNP biogenesis. Signal recognition particle (SRP) is a ribonucleoprotein particle crucial for co-t...

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Detalles Bibliográficos
Autores principales:	Piazzon, Nathalie, Schlotter, Florence, Lefebvre, Suzie, Dodré, Maxime, Méreau, Agnès, Soret, Johann, Besse, Aurore, Barkats, Martine, Bordonné, Rémy, Branlant, Christiane, Massenet, Séverine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553995/ https://www.ncbi.nlm.nih.gov/pubmed/23221635 http://dx.doi.org/10.1093/nar/gks1224

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