Cargando…

A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk

We assessed the role of rare copy number variants (CNVs) in Alzheimer's disease (AD) using intensity data from 3260 AD cases and 1290 age-matched controls from the genome-wide association study (GWAS) conducted by the Genetic and Environmental Risk for Alzheimer's disease Consortium (GERAD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chapman, Jade, Rees, Elliott, Harold, Denise, Ivanov, Dobril, Gerrish, Amy, Sims, Rebecca, Hollingworth, Paul, Stretton, Alexandra, Holmans, Peter, Owen, Michael J., O'Donovan, Michael C., Williams, Julie, Kirov, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Association Studies Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554198/ https://www.ncbi.nlm.nih.gov/pubmed/23148125 http://dx.doi.org/10.1093/hmg/dds476

Ejemplares similares

De novo CNVs in bipolar affective disorder and schizophrenia
por: Georgieva, Lyudmila, et al.
Publicado: (2014)

Association of Rare Copy Number Variants With Risk of Depression
por: Kendall, Kimberley Marie, et al.
Publicado: (2019)

Copy number variation and neuropsychiatric illness
por: Rees, Elliott, et al.
Publicado: (2021)

A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder
por: Martin, Joanna, et al.
Publicado: (2020)

Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank
por: Kendall, Kimberley M., et al.
Publicado: (2019)

Schizophrenia copy number variants and associative learning
por: Clifton, N E, et al.
Publicado: (2017)

Analysis of copy number variations at 15 schizophrenia-associated loci
por: Rees, Elliott, et al.
Publicado: (2014)

A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia
por: Hall, Lynsey S, et al.
Publicado: (2020)

Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia
por: Rammos, Alexandros, et al.
Publicado: (2023)

Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants
por: Langley, Kate, et al.
Publicado: (2011)

Copy number variation in bipolar disorder
por: Green, E K, et al.
Publicado: (2016)

Association of copy number variation across the genome with neuropsychiatric traits in the general population
por: Guyatt, Anna L., et al.
Publicado: (2018)

Gender differences in CNV burden do not confound schizophrenia CNV associations
por: Han, Jun, et al.
Publicado: (2016)

Biological Overlap of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: Evidence From Copy Number Variants
por: Martin, Joanna, et al.
Publicado: (2014)

Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank
por: Warland, Anthony, et al.
Publicado: (2019)

Copy number, linkage disequilibrium and disease association in the FCGR locus
por: Niederer, Heather A., et al.
Publicado: (2010)

No evidence for association between polymorphisms in GRM3 and schizophrenia
por: Norton, Nadine, et al.
Publicado: (2005)

Exome arrays capture polygenic rare variant contributions to schizophrenia
por: Richards, A. L., et al.
Publicado: (2016)

Analysis of copy number variation using quantitative interspecies competitive PCR
por: Williams, Nigel M., et al.
Publicado: (2008)

No Evidence for Enrichment in Schizophrenia for Common Allelic Associations at Imprinted Loci
por: Escott-Price, Valentina, et al.
Publicado: (2015)

A Polynesian-specific copy number variant encompassing the MICA gene associates with gout
por: Wang, Ke, et al.
Publicado: (2022)

Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing
por: Crawford, Karen, et al.
Publicado: (2022)

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes
por: Cooper, Nicholas J., et al.
Publicado: (2015)

Pathogenic copy number variants and SCN1A mutations in patients with intellectual disability and childhood-onset epilepsy
por: Fry, Andrew E., et al.
Publicado: (2016)

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1
por: Rees, Elliott, et al.
Publicado: (2014)

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
por: Rees, Elliott, et al.
Publicado: (2021)

Genetic association of FMRP targets with psychiatric disorders
por: Clifton, Nicholas E., et al.
Publicado: (2020)

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank
por: Owen, David, et al.
Publicado: (2018)

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis
por: Jarick, Ivonne, et al.
Publicado: (2011)

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia
por: Pocklington, Andrew J., et al.
Publicado: (2015)

Ultrarare Coding Variants and Cognitive Function in Schizophrenia
por: Creeth, Hugo D. J., et al.
Publicado: (2022)

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
por: Abraham, Richard, et al.
Publicado: (2008)

Show your support for our resolutions...by electronic vote
por: Staff Association
Publicado: (2005)

Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank
por: Caseras, Xavier, et al.
Publicado: (2021)

Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK biobank
por: Bracher-Smith, Matthew, et al.
Publicado: (2022)

Copy Number Variants Increasing Risk for Schizophrenia: Shared and Distinct Effects on Brain Morphometry and Cognitive Performance
por: Caseras, Xavier, et al.
Publicado: (2022)

A comparison of four clustering methods for brain expression microarray data
por: Richards, Alexander L, et al.
Publicado: (2008)

Common alleles contribute to schizophrenia in CNV carriers
por: Tansey, K E, et al.
Publicado: (2016)

Erratum: Common alleles contribute to schizophrenia in CNV carriers
por: Tansey, K E, et al.
Publicado: (2015)

Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression
por: Roszik, Jason, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0jqi30oem7lu99rv53numtalsp