Oncogenic FGFR3 gene fusions in bladder cancer

FGF receptor 3 (FGFR3) is activated by mutation or over-expression in many bladder cancers. Here, we identify an additional mechanism of activation via chromosomal re-arrangement to generate constitutively activated fusion genes. FGFR3–transforming acid coiled coil 3 (TACC3) fusions resulting from 4...

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Detalles Bibliográficos
Autores principales: Williams, Sarah V., Hurst, Carolyn D., Knowles, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554204/
https://www.ncbi.nlm.nih.gov/pubmed/23175443
http://dx.doi.org/10.1093/hmg/dds486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554204/
https://www.ncbi.nlm.nih.gov/pubmed/23175443
http://dx.doi.org/10.1093/hmg/dds486

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