Cargando…

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

Common diseases such as endometriosis (ED), Alzheimer's disease (AD) and multiple sclerosis (MS) account for a significant proportion of the health care burden in many countries. Genome-wide association studies (GWASs) for these diseases have identified a number of individual genetic variants c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, S. Hong, Harold, Denise, Nyholt, Dale R., Goddard, Michael E., Zondervan, Krina T., Williams, Julie, Montgomery, Grant W., Wray, Naomi R., Visscher, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Association Studies Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554206/ https://www.ncbi.nlm.nih.gov/pubmed/23193196 http://dx.doi.org/10.1093/hmg/dds491

Ejemplares similares

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci
por: Rahmioglu, Nilufer, et al.
Publicado: (2015)

Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
por: Rahmioglu, Nilufer, et al.
Publicado: (2014)

No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis
por: Luong, Hien T.T., et al.
Publicado: (2012)

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis
por: Uimari, Outi, et al.
Publicado: (2017)

Insights into Assessing the Genetics of Endometriosis
por: Rahmioglu, Nilufer, et al.
Publicado: (2012)

A Simple and Fast Two-Locus Quality Control Test to Detect False Positives Due to Batch Effects in Genome-Wide Association Studies
por: Lee, Sang Hong, et al.
Publicado: (2010)

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
por: Lee, S Hong, et al.
Publicado: (2012)

Exome arrays capture polygenic rare variant contributions to schizophrenia
por: Richards, A. L., et al.
Publicado: (2016)

Multiplex melanoma families are enriched for polygenic risk
por: Law, Matthew H, et al.
Publicado: (2020)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research
por: Becker, Christian M., et al.
Publicado: (2014)

Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis
por: Painter, Jodie N., et al.
Publicado: (2010)

Priorities for Endometriosis Research: Recommendations From an International Consensus Workshop
por: Rogers, Peter A. W., et al.
Publicado: (2009)

Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
por: McGrath, Isabelle M., et al.
Publicado: (2023)

Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity
por: Adewuyi, Emmanuel O., et al.
Publicado: (2020)

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
por: Hegele, Robert A., et al.
Publicado: (2009)

Genome-wide association meta-analysis identifies new endometriosis risk loci
por: Nyholt, Dale R., et al.
Publicado: (2012)

The future for genetic studies in reproduction
por: Montgomery, G.W., et al.
Publicado: (2014)

Improved polygenic prediction by Bayesian multiple regression on summary statistics
por: Lloyd-Jones, Luke R., et al.
Publicado: (2019)

Polygenic Risk Score Prediction for Endometriosis
por: Kloeve-Mogensen, Kirstine, et al.
Publicado: (2021)

Embracing polygenicity: a review of methods and tools for psychiatric genetics research
por: Maier, R. M., et al.
Publicado: (2018)

Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases
por: Howe, Laurence J, et al.
Publicado: (2020)

Is early age at menarche a risk factor for endometriosis? A systematic review and meta-analysis of case-control studies
por: Nnoaham, Kelechi E., et al.
Publicado: (2012)

Developing symptom-based predictive models of endometriosis as a clinical screening tool: results from a multicenter study
por: Nnoaham, Kelechi E., et al.
Publicado: (2012)

The role of gene polymorphisms in endometriosis
por: Matalliotakis, Michail, et al.
Publicado: (2017)

Using Polygenic Scores in Social Science Research: Unraveling Childlessness
por: Verweij, Renske M., et al.
Publicado: (2019)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research
por: Fassbender, Amelie, et al.
Publicado: (2014)

Impact of Endometriosis in Women of Arab Ancestry on: Health-Related Quality of Life, Work Productivity, and Diagnostic Delay
por: Mousa, Mira, et al.
Publicado: (2021)

Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks
por: Zhao, Huiying, et al.
Publicado: (2017)

Large-scale meta-analysis highlights the hypothalamic–pituitary–gonadal axis in the genetic regulation of menstrual cycle length
por: Laisk, Triin, et al.
Publicado: (2018)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23
por: Orozco, Gisela, et al.
Publicado: (2009)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research
por: Rahmioglu, Nilufer, et al.
Publicado: (2014)

Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions
por: Viana, Joana, et al.
Publicado: (2017)

The role of IL-16 gene polymorphisms in endometriosis
por: Matalliotakis, Michail, et al.
Publicado: (2018)

The miRNA Mirage: How Close Are We to Finding a Non-Invasive Diagnostic Biomarker in Endometriosis? A Systematic Review
por: Agrawal, Swati, et al.
Publicado: (2018)

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium
por: Milne, Roger L., et al.
Publicado: (2014)

World Endometriosis Research Foundation Endometriosis Phenome and biobanking harmonization project: II. Clinical and covariate phenotype data collection in endometriosis research
por: Vitonis, Allison F., et al.
Publicado: (2014)

Characterization of exosomes in peritoneal fluid of endometriosis patients
por: Nazri, Hannah M., et al.
Publicado: (2020)

How well do HapMap SNPs capture the untyped SNPs?
por: Tantoso, Erwin, et al.
Publicado: (2006)

An international terminology for endometriosis, 2021(,)
por: Tomassetti, Carla, et al.
Publicado: (2021)

Applicability of polygenic risk scores in endometriosis clinical presentation
por: Svensson, Agnes, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8tpa168n9nn59jeeiplq5e2cu8