Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance

Dysregulated lipid metabolism and inflammation are linked to the development of insulin resistance in obesity, and the intracellular accumulation of the sphingolipid ceramide has been implicated in these processes. Here, we explored the role of circulating ceramide on the pathogenesis of insulin res...

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Detalles Bibliográficos
Autores principales: Boon, James, Hoy, Andrew J., Stark, Romana, Brown, Russell D., Meex, Ruth C., Henstridge, Darren C., Schenk, Simon, Meikle, Peter J., Horowitz, Jeffrey F., Kingwell, Bronwyn A., Bruce, Clinton R., Watt, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554351/
https://www.ncbi.nlm.nih.gov/pubmed/23139352
http://dx.doi.org/10.2337/db12-0686

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