Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of τ Protein Following Onset of Diabetes in NOD Mice

The histopathological hallmarks of Alzheimer disease (AD) include intraneuronal neurofibrillary tangles composed of abnormally hyperphosphorylated τ protein. Insulin dysfunction might influence AD pathology, as population-based and cohort studies have detected higher AD incidence rates in diabetic p...

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Detalles Bibliográficos
Autores principales: Papon, Marie-Amélie, El Khoury, Noura B., Marcouiller, François, Julien, Carl, Morin, Françoise, Bretteville, Alexis, Petry, Franck R., Gaudreau, Simon, Amrani, Abdelaziz, Mathews, Paul M., Hébert, Sébastien S., Planel, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554372/
https://www.ncbi.nlm.nih.gov/pubmed/22961084
http://dx.doi.org/10.2337/db12-0187

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