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The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human

We provide the first comprehensive analysis of the extracellular matrix (ECM) composition of peri-islet capsules, composed of the peri-islet basement membrane (BM) and subjacent interstitial matrix (IM), in development of type 1 diabetes in NOD mice and in human type 1 diabetes. Our data demonstrate...

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Detalles Bibliográficos
Autores principales: Korpos, Éva, Kadri, Nadir, Kappelhoff, Reinhild, Wegner, Jeannine, Overall, Christopher M., Weber, Ekkehard, Holmberg, Dan, Cardell, Susanna, Sorokin, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554379/
https://www.ncbi.nlm.nih.gov/pubmed/23139348
http://dx.doi.org/10.2337/db12-0432