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Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model

BACKGROUND: Intraclass correlation coefficients (ICCs) are used in a wide range of applications. However, most commonly used estimators for the ICC are known to be subject to bias. METHODS: Using second order Taylor series expansion, we propose a new bias-corrected estimator for one type of intracla...

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Autores principales: Atenafu, Eshetu G, Hamid, Jemila S, To, Teresa, Willan, Andrew R, M Feldman, Brian, Beyene, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554464/
https://www.ncbi.nlm.nih.gov/pubmed/22905752
http://dx.doi.org/10.1186/1471-2288-12-126
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author Atenafu, Eshetu G
Hamid, Jemila S
To, Teresa
Willan, Andrew R
M Feldman, Brian
Beyene, Joseph
author_facet Atenafu, Eshetu G
Hamid, Jemila S
To, Teresa
Willan, Andrew R
M Feldman, Brian
Beyene, Joseph
author_sort Atenafu, Eshetu G
collection PubMed
description BACKGROUND: Intraclass correlation coefficients (ICCs) are used in a wide range of applications. However, most commonly used estimators for the ICC are known to be subject to bias. METHODS: Using second order Taylor series expansion, we propose a new bias-corrected estimator for one type of intraclass correlation coefficient, for the ICC that arises in the context of the balanced one-way random effects model. A simulation study is performed to assess the performance of the proposed estimator. Data have been generated under normal as well as non-normal scenarios. RESULTS: Our simulation results show that the new estimator has reduced bias compared to the least square estimator which is often referred to as the conventional or analytical estimator. The results also show marked bias reduction both in normal and non-normal data scenarios. In particular, our estimator outperforms the analytical estimator in a non-normal setting producing estimates that are very close to the true ICC values. CONCLUSIONS: The proposed bias-corrected estimator for the ICC from a one-way random effects analysis of variance model appears to perform well in the scenarios we considered in this paper and can be used as a motivation to construct bias-corrected estimators for other types of ICCs that arise in more complex scenarios. It would also be interesting to investigate the bias-variance trade-off.
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spelling pubmed-35544642013-01-29 Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model Atenafu, Eshetu G Hamid, Jemila S To, Teresa Willan, Andrew R M Feldman, Brian Beyene, Joseph BMC Med Res Methodol Research Article BACKGROUND: Intraclass correlation coefficients (ICCs) are used in a wide range of applications. However, most commonly used estimators for the ICC are known to be subject to bias. METHODS: Using second order Taylor series expansion, we propose a new bias-corrected estimator for one type of intraclass correlation coefficient, for the ICC that arises in the context of the balanced one-way random effects model. A simulation study is performed to assess the performance of the proposed estimator. Data have been generated under normal as well as non-normal scenarios. RESULTS: Our simulation results show that the new estimator has reduced bias compared to the least square estimator which is often referred to as the conventional or analytical estimator. The results also show marked bias reduction both in normal and non-normal data scenarios. In particular, our estimator outperforms the analytical estimator in a non-normal setting producing estimates that are very close to the true ICC values. CONCLUSIONS: The proposed bias-corrected estimator for the ICC from a one-way random effects analysis of variance model appears to perform well in the scenarios we considered in this paper and can be used as a motivation to construct bias-corrected estimators for other types of ICCs that arise in more complex scenarios. It would also be interesting to investigate the bias-variance trade-off. BioMed Central 2012-08-20 /pmc/articles/PMC3554464/ /pubmed/22905752 http://dx.doi.org/10.1186/1471-2288-12-126 Text en Copyright ©2012 Atenafu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Atenafu, Eshetu G
Hamid, Jemila S
To, Teresa
Willan, Andrew R
M Feldman, Brian
Beyene, Joseph
Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title_full Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title_fullStr Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title_full_unstemmed Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title_short Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
title_sort bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554464/
https://www.ncbi.nlm.nih.gov/pubmed/22905752
http://dx.doi.org/10.1186/1471-2288-12-126
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