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IL-11 produced by breast cancer cells augments osteoclastogenesis by sustaining the pool of osteoclast progenitor cells

BACKGROUND: Interleukin (IL)-11, a cytokine produced by breast cancer, has been implicated in breast cancer-induced osteolysis (bone destruction) but the mechanism(s) of action remain controversial. Some studies show that IL-11 is able to promote osteoclast formation independent of the receptor acti...

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Detalles Bibliográficos
Autores principales:	McCoy, Erin M, Hong, Huixian, Pruitt, Hawley C, Feng, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554506/ https://www.ncbi.nlm.nih.gov/pubmed/23311882 http://dx.doi.org/10.1186/1471-2407-13-16

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