Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences

Pax6 is a developmental control gene essential for eye development throughout the animal kingdom. In addition, Pax6 plays key roles in other parts of the CNS, olfactory system, and pancreas. In mammals a single Pax6 gene encoding multiple isoforms delivers these pleiotropic functions. Here we provid...

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Detalles Bibliográficos
Autores principales: Ravi, Vydianathan, Bhatia, Shipra, Gautier, Philippe, Loosli, Felix, Tay, Boon-Hui, Tay, Alice, Murdoch, Emma, Coutinho, Pedro, van Heyningen, Veronica, Brenner, Sydney, Venkatesh, Byrappa, Kleinjan, Dirk A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554528/
https://www.ncbi.nlm.nih.gov/pubmed/23359656
http://dx.doi.org/10.1371/journal.pgen.1003177

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