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Heterologous Gln/Asn-Rich Proteins Impede the Propagation of Yeast Prions by Altering Chaperone Availability

Prions are self-propagating conformations of proteins that can cause heritable phenotypic traits. Most yeast prions contain glutamine (Q)/asparagine (N)-rich domains that facilitate the accumulation of the protein into amyloid-like aggregates. Efficient transmission of these infectious aggregates to...

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Detalles Bibliográficos
Autores principales:	Yang, Zi, Hong, Joo Y., Derkatch, Irina L., Liebman, Susan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554615/ https://www.ncbi.nlm.nih.gov/pubmed/23358669 http://dx.doi.org/10.1371/journal.pgen.1003236

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