Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3(+)CCR6(+) Th1 Subset

An understanding of the immunological footprint of Mycobacterium tuberculosis (MTB) CD4 T cell recognition is still incomplete. Here we report that human Th1 cells specific for MTB are largely contained in a CXCR3(+)CCR6(+) memory subset and highly focused on three broadly immunodominant antigenic i...

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Detalles Bibliográficos
Autores principales: Lindestam Arlehamn, Cecilia S., Gerasimova, Anna, Mele, Federico, Henderson, Ryan, Swann, Justine, Greenbaum, Jason A., Kim, Yohan, Sidney, John, James, Eddie A., Taplitz, Randy, McKinney, Denise M., Kwok, William W., Grey, Howard, Sallusto, Federica, Peters, Bjoern, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554618/
https://www.ncbi.nlm.nih.gov/pubmed/23358848
http://dx.doi.org/10.1371/journal.ppat.1003130

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