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A Novel Mechanism of Formaldehyde Neurotoxicity: Inhibition of Hydrogen Sulfide Generation by Promoting Overproduction of Nitric Oxide

BACKGROUND: Formaldehyde (FA) induces neurotoxicity by overproduction of intracellular reactive oxygen species (ROS). Increasing studies have shown that hydrogen sulfide (H(2)S), an endogenous gastransmitter, protects nerve cells against oxidative stress by its antioxidant effect. It has been shown...

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Detalles Bibliográficos
Autores principales:	Tang, Xiao-Qing, Fang, Heng-Rong, Zhou, Cheng-Fang, Zhuang, Yuan-Yuan, Zhang, Ping, Gu, Hong-Feng, Hu, Bi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554621/ https://www.ncbi.nlm.nih.gov/pubmed/23359814 http://dx.doi.org/10.1371/journal.pone.0054829

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