Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway

Our previous studies showed positive correlation between accumulation of proNGF, activation of RhoA and neuronal death in diabetic models. Here, we examined the neuroprotective effects of selective inhibition of RhoA kinase in the diabetic rat retina and in a model that stably overexpressed the clea...

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Detalles Bibliográficos
Autores principales: Al-Gayyar, Mohammed M. H., Mysona, Barbara A., Matragoon, Suraporn, Abdelsaid, Mohammed A., El-Azab, Mona F., Shanab, Ahmed Y., Ha, Yonju, Smith, Sylvia B., Bollinger, Kathryn E., El-Remessy, Azza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554698/
https://www.ncbi.nlm.nih.gov/pubmed/23365678
http://dx.doi.org/10.1371/journal.pone.0054692

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