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Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration

BACKGROUND: Mitochondrial dysfunction is associated with the development and progression of age-related macular degeneration (AMD). Recent studies using populations from the United States and Australia have demonstrated that AMD is associated with mitochondrial (mt) DNA haplogroups (as defined by co...

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Detalles Bibliográficos
Autores principales:	Kenney, M. Cristina, Chwa, Marilyn, Atilano, Shari R., Pavlis, Janelle M., Falatoonzadeh, Payam, Ramirez, Claudio, Malik, Deepika, Hsu, Tiffany, Woo, Grace, Soe, Kyaw, Nesburn, Anthony B., Boyer, David S., Kuppermann, Baruch D., Jazwinski, S. Michal, Miceli, Michael V., Wallace, Douglas C., Udar, Nitin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554762/ https://www.ncbi.nlm.nih.gov/pubmed/23365660 http://dx.doi.org/10.1371/journal.pone.0054339

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