Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation

Rapidly growing tumor cells require a nutrient-rich environment in order to thrive, therefore, restricting access to certain key amino acids, such as arginine, often results in the death of malignant cells, which frequently display defective cell cycle check-point control. Healthy cells, by contrast...

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Detalles Bibliográficos
Autores principales: Wells, James W., Evans, Christopher H., Scott, Milcah C., Rütgen, Barbara C., O'Brien, Timothy D., Modiano, Jaime F., Cvetkovic, Goran, Tepic, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554772/
https://www.ncbi.nlm.nih.gov/pubmed/23365669
http://dx.doi.org/10.1371/journal.pone.0054464

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