RNAi triggered by specialized machinery silences developmental genes and retrotransposons

RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats(1,2). However, the full extent of RNAi functions and its endogenous targets have not been exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamanaka, Soichiro, Mehta, Sameet, Reyes-Turcu, Francisca E., Zhuang, Fanglei, Fuchs, Ryan T., Rong, Yikang, Robb, Gregory B., Grewal, Shiv I. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554839/
https://www.ncbi.nlm.nih.gov/pubmed/23151475
http://dx.doi.org/10.1038/nature11716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554839/
https://www.ncbi.nlm.nih.gov/pubmed/23151475
http://dx.doi.org/10.1038/nature11716

Ejemplares similares