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Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man

Central pontine myelinolysis is a demyelinating condition affecting the pons characterized by an acute progressive quadriplegia, dysarthria, dysphagia, and alterations of consciousness. Pathologic features include prominent demyelination in the central pons with sparing of axons and neurons. This co...

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Detalles Bibliográficos
Autores principales: Gupta, Rishab, Balhara, Yatan Pal Singh, Sagar, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555017/
https://www.ncbi.nlm.nih.gov/pubmed/23372330
http://dx.doi.org/10.4103/0976-7800.104475
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author Gupta, Rishab
Balhara, Yatan Pal Singh
Sagar, Rajesh
author_facet Gupta, Rishab
Balhara, Yatan Pal Singh
Sagar, Rajesh
author_sort Gupta, Rishab
collection PubMed
description Central pontine myelinolysis is a demyelinating condition affecting the pons characterized by an acute progressive quadriplegia, dysarthria, dysphagia, and alterations of consciousness. Pathologic features include prominent demyelination in the central pons with sparing of axons and neurons. This condition is usually associated with systemic disorders such as hyponatremia, chronic alcoholism, liver failure, severe burns, malignant neoplasms, hemorrhagic pancreatitis, hemodialysis, and sepsis. There are limited reports of psychosis in patients with central pontine/extrapontine myelinolysis (CPEM). We have described a case of CPEM with psychosis as a complication which recovered completely with treatment given for short duration using low dose atypical antipsychotic (quetiapine). We also discuss etiopathology and clinical outcome of psychosis in this rare neurological disorder.
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spelling pubmed-35550172013-01-31 Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man Gupta, Rishab Balhara, Yatan Pal Singh Sagar, Rajesh J Midlife Health Case Report Central pontine myelinolysis is a demyelinating condition affecting the pons characterized by an acute progressive quadriplegia, dysarthria, dysphagia, and alterations of consciousness. Pathologic features include prominent demyelination in the central pons with sparing of axons and neurons. This condition is usually associated with systemic disorders such as hyponatremia, chronic alcoholism, liver failure, severe burns, malignant neoplasms, hemorrhagic pancreatitis, hemodialysis, and sepsis. There are limited reports of psychosis in patients with central pontine/extrapontine myelinolysis (CPEM). We have described a case of CPEM with psychosis as a complication which recovered completely with treatment given for short duration using low dose atypical antipsychotic (quetiapine). We also discuss etiopathology and clinical outcome of psychosis in this rare neurological disorder. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3555017/ /pubmed/23372330 http://dx.doi.org/10.4103/0976-7800.104475 Text en Copyright: © Journal of Mid-life Health http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gupta, Rishab
Balhara, Yatan Pal Singh
Sagar, Rajesh
Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title_full Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title_fullStr Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title_full_unstemmed Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title_short Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
title_sort acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555017/
https://www.ncbi.nlm.nih.gov/pubmed/23372330
http://dx.doi.org/10.4103/0976-7800.104475
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