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Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model

BACKGROUND: Defects in keratinocyte differentiation and skin barrier are important features of inflammatory skin diseases like atopic dermatitis. Mast cells and their main mediator histamine are abundant in inflamed skin and thus may contribute to disease pathogenesis. METHODS: Human primary keratin...

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Detalles Bibliográficos
Autores principales:	Gschwandtner, M, Mildner, M, Mlitz, V, Gruber, F, Eckhart, L, Werfel, T, Gutzmer, R, Elias, P M, Tschachler, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555427/ https://www.ncbi.nlm.nih.gov/pubmed/23157658 http://dx.doi.org/10.1111/all.12051

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