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Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism

Novel classes of pain-relieving molecules are needed to fill the void between non-steroidal anti-inflammatory agents and narcotics. We have recently shown that intraplantar administration of sphingosine 1-phosphate (S1P) in rats causes peripheral sensitization and hyperalgesia through the S1P(1) rec...

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Detalles Bibliográficos
Autores principales:	Finley, Amanda, Chen, Zhoumou, Esposito, Emanuela, Cuzzocrea, Salvatore, Sabbadini, Roger, Salvemini, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555820/ https://www.ncbi.nlm.nih.gov/pubmed/23372844 http://dx.doi.org/10.1371/journal.pone.0055255

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