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The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation

BACKGROUND: Toll like receptors (TLRs) sense the intestinal microbiota and regulate the innate immune response. A dysregulation of TLRs function participates into intestinal inflammation. Farnesoid X Receptor (FXR) is a nuclear receptor and bile acid sensor highly expressed in entero-hepatic tissues...

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Detalles Bibliográficos
Autores principales:	Renga, Barbara, Mencarelli, Andrea, Cipriani, Sabrina, D'Amore, Claudio, Carino, Adriana, Bruno, Angela, Francisci, Daniela, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555871/ https://www.ncbi.nlm.nih.gov/pubmed/23372731 http://dx.doi.org/10.1371/journal.pone.0054472

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