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Chitosan and chitosan chlorhydrate based various approaches for enhancement of dissolution rate of carvedilol

BACKGROUND AND THE PURPOSE OF THE STUDY: Carvedilol nonselective β-adrenoreceptor blocker, chemically (±)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxypHenoxy) ethyl] amino]-2-propanol, slightly soluble in ethyl ether; and practically insoluble in water, gastric fluid (simulated, TS, pH 1.1), and intestinal...

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Detalles Bibliográficos
Autores principales: Shete, Amol S, Yadav, Adhikrao V, Murthy, Srinivasa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556008/
https://www.ncbi.nlm.nih.gov/pubmed/23351907
http://dx.doi.org/10.1186/2008-2231-20-93

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