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A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study
BACKGROUND AND THE PURPOSE OF THE STUDY: Adenosine deaminase (ADA) inhibition not only may be applied for the treatment of ischemic injury, hypertension, lymphomas and leukaemia, but also they have been considered as anti- inflammatory drugs. On the other hand according to literatures, ADA inhibitor...
Autores principales: | Bazl, Roya, Ganjali, Mohammad Reza, Saboury, Ali-akbar, Foroumadi, Alireza, Nourozi, Parviz, Amanlou, Massoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556010/ https://www.ncbi.nlm.nih.gov/pubmed/23351306 http://dx.doi.org/10.1186/2008-2231-20-64 |
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