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Metformin loaded non-ionic surfactant vesicles: optimization of formulation, effect of process variables and characterization
BACKGROUND: Metformin an oral hypoglycemic has been widely used as a fist line of treatment of Type II Diabetes but in a very high dose 2–3 times a day and moreover suffers from a number of side effects like lactic acidosis, gastric discomfort, chest pain, allergic reactions being some of them. The...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556082/ https://www.ncbi.nlm.nih.gov/pubmed/23351604 http://dx.doi.org/10.1186/2008-2231-21-7 |