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Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains
Transcription activator-like effectors (TALE) are sequence-specific DNA binding proteins that harbor modular, repetitive DNA binding domains. TALEs have enabled the creation of customizable designer transcriptional factors and sequence-specific nucleases for genome engineering. Here we report two im...
Autores principales: | Cong, Le, Zhou, Ruhong, Kuo, Yu-chi, Cunniff, Margaret, Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556390/ https://www.ncbi.nlm.nih.gov/pubmed/22828628 http://dx.doi.org/10.1038/ncomms1962 |
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